Circadian clocks: self-assembling oscillators?
نویسندگان
چکیده
منابع مشابه
Circadian clocks: self-assembling oscillators?
Circadian clocks are auto-regulatory loops in which 'clock' gene products feedback to regulate their own expression. This explains how they keep oscillating, but how do they first get going? It appears that the transcription factor dClock not only drives the oscillation within the fruit fly's clock, but also plays a pivotal role in pre-assembling the clockwork.
متن کاملCircadian Biology: Clocks within Clocks
A small cluster of approximately 20,000 neurons in the ventral hypothalamus provide the body with key time-keeping signals and drive circadian rhythms. This circadian clock exhibits surprisingly complex substructures, with inputs from the retina, and outputs to other brain structures. Rather little is known of the neurotransmitters involved, or their regulation.
متن کاملCircadian clocks
The biological world is not static: organisms inhabit environments which change predictably over the course of the day and night. There will therefore be selective advantage to any individuals able to anticipate these changes and attune their physiology and behaviour accordingly. Anticipation of daily cycles is conferred by endogenous timers, biological clocks with an intrinsic period of approx...
متن کاملFeeding and circadian clocks.
The mammalian genome encodes at least a dozen of genes directly involved in the regulation of the feedback loops constituting the circadian clock. The circadian system is built up on a multitude of oscillators organized according to a hierarchical model in which neurons of the suprachiasmatic nuclei of the hypothalamus may drive the central circadian clock and all the other somatic cells may po...
متن کاملCircadian Clocks and Pregnancy
The recognition that 24-h rhythmic processes (“circadian”) underlie many endocrine functions has added a fascinating new temporal dimension to our appreciation of their complexity. Research from various laboratories has revealed circadian gene expression in multiple tissues in the reproductive system of non-pregnant and pregnant mammals. However, many questions regarding role of circadian clock...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Current Biology
سال: 2003
ISSN: 0960-9822
DOI: 10.1016/s0960-9822(03)00608-0